Repeated-outcome longitudinal TMLE#

This study validates LTMLE with outcome=Repeated(["Y1", "Y2", "Y3"]). A repeated outcome is measured at every node and is not absorbing. The parameter is the mean \(E[Y_h^d]\) for each plan \(d\) and horizon \(h\). The section repeated outcomes states the estimator and its exact-law evidence. The declared comparator is R ltmle 1.3-0 with survivalOutcome = FALSE.

Its runs are pending as TRACKER Study queue item 14(c). This page holds Python property evidence, with comparator runs pending.

The study reports each unique parameter once. The dynamic plan equals the always-treated plan at the first node, so its mean and contrast at \(t = 1\) duplicate those of always. A fast test checks that identity. The duplicates are not cells of this study.

What was compared#

The R column states the declared design of the pending comparator runs.

setting

cleverly

R ltmle

datasets

2,400 censored panels of 3,000 rows from make_longitudinal_repeated, with three nodes

the identical rows

fit

one fit with outcome=Repeated(["Y1", "Y2", "Y3"])

one fit of the prefix through \(Y_h\) for each horizon \(h\). The earlier \(Y_s\) are covariates

plans

never, always, and a rule that treats at node 1 and then treats exactly when the previous outcome was positive

the same three plans

reported parameters

the mean of each plan at \(t = 1, 2, 3\), and the contrasts of the other two plans against never

the same, 13 unique cells

mechanism

the generating treatment and censoring probabilities, read through a declared design width, with g_bounds from the study constant

a numeric gform with the same probabilities and bounds

sequential regressions

follower-stratified quasibinomial regressions on the history at each node

the same family, with a main-terms Qform on the same history at each block

fitting

in sample, n_folds = 1

in sample

intervals

pointwise 95% Wald from the influence curve

variance.method = "ic"

initial estimate

not published. A single-fold fit exposes no untargeted plug-in

a second call with gcomp = TRUE, the sequential regression with no fluctuation

The cleverly rows publish no initial estimate. The first node’s regression of the targeted chain is a different quantity from the R column. The R plug-in is the value a targeting step must move away from.

Each truth is an exact enumeration of the binary law (cleverly.datasets.repeated_truth). tests/studies/ltmle_repeated_law.py repeats the enumeration on the observed-data law.

The baseline covariate \(W\) takes the values 0, 1 and 2. The law has depth two. The treatment, censoring and outcome at node \(t\) read \(Y_{t-2}\). The covariate \(L_t\) reads \(L_{t-1}\), and the outcome \(Y_t\) also reads \(L_{t-1}\). These terms act at \(t = 3\) only. The first node’s regression on \(W\) has one design column for three cells, so its fluctuation is not zero.

At \(t = 3\) the smallest cumulative mechanism product among the units that follow a plan is 0.025, for the rule. Every plan keeps at least 11% of the units to the last node. At most 2.2% of the followers have a cumulative product below 0.05.

Accuracy against known truth#

law

estimand

what was tested

implementation

bias (99% interval)

coverage

SE ratio

result

three-time-point law with a three-valued baseline covariate, a repeated binary outcome that reads the two previous nodes, and monotone censoring

ate_regimen[always vs never @ t=1]

difference in the mean of the repeated outcome between the plans “treat at every time” against “treat at no time” at horizon t = 1

cleverly

-0.000963 to 0.000622

0.9442

0.9791

pass

three-time-point law with a three-valued baseline covariate, a repeated binary outcome that reads the two previous nodes, and monotone censoring

ate_regimen[always vs never @ t=2]

difference in the mean of the repeated outcome between the plans “treat at every time” against “treat at no time” at horizon t = 2

cleverly

-0.0012 to 0.000960

0.9529

1.0090

pass

three-time-point law with a three-valued baseline covariate, a repeated binary outcome that reads the two previous nodes, and monotone censoring

ate_regimen[always vs never @ t=3]

difference in the mean of the repeated outcome between the plans “treat at every time” against “treat at no time” at horizon t = 3

cleverly

-0.0012 to 0.0021

0.9483

0.9930

pass

three-time-point law with a three-valued baseline covariate, a repeated binary outcome that reads the two previous nodes, and monotone censoring

ate_regimen[treat then treat after an outcome vs never @ t=2]

difference in the mean of the repeated outcome between the plans “treat at the first time, then treat at each later time after an outcome of one” against “treat at no time” at horizon t = 2

cleverly

-0.0013 to 0.000903

0.9567

1.0266

pass

three-time-point law with a three-valued baseline covariate, a repeated binary outcome that reads the two previous nodes, and monotone censoring

ate_regimen[treat then treat after an outcome vs never @ t=3]

difference in the mean of the repeated outcome between the plans “treat at the first time, then treat at each later time after an outcome of one” against “treat at no time” at horizon t = 3

cleverly

-0.0018 to 0.0018

0.9387

0.9625

pass

three-time-point law with a three-valued baseline covariate, a repeated binary outcome that reads the two previous nodes, and monotone censoring

ey_regimen[always @ t=1]

mean of the repeated outcome under the plan treat at every time at horizon t = 1

cleverly

-0.000482 to 0.000368

0.9496

0.9964

pass

three-time-point law with a three-valued baseline covariate, a repeated binary outcome that reads the two previous nodes, and monotone censoring

ey_regimen[always @ t=2]

mean of the repeated outcome under the plan treat at every time at horizon t = 2

cleverly

-0.0011 to 0.000149

0.9454

0.9993

pass

three-time-point law with a three-valued baseline covariate, a repeated binary outcome that reads the two previous nodes, and monotone censoring

ey_regimen[always @ t=3]

mean of the repeated outcome under the plan treat at every time at horizon t = 3

cleverly

-0.000869 to 0.0012

0.9387

0.9786

pass

three-time-point law with a three-valued baseline covariate, a repeated binary outcome that reads the two previous nodes, and monotone censoring

ey_regimen[never @ t=1]

mean of the repeated outcome under the plan treat at no time at horizon t = 1

cleverly

-0.000552 to 0.000779

0.9508

0.9786

pass

three-time-point law with a three-valued baseline covariate, a repeated binary outcome that reads the two previous nodes, and monotone censoring

ey_regimen[never @ t=2]

mean of the repeated outcome under the plan treat at no time at horizon t = 2

cleverly

-0.0012 to 0.000485

0.9433

1.0014

pass

three-time-point law with a three-valued baseline covariate, a repeated binary outcome that reads the two previous nodes, and monotone censoring

ey_regimen[never @ t=3]

mean of the repeated outcome under the plan treat at no time at horizon t = 3

cleverly

-0.0015 to 0.0010

0.9529

0.9863

pass

three-time-point law with a three-valued baseline covariate, a repeated binary outcome that reads the two previous nodes, and monotone censoring

ey_regimen[treat then treat after an outcome @ t=2]

mean of the repeated outcome under the plan treat at the first time, then treat at each later time after an outcome of one at horizon t = 2

cleverly

-0.0013 to 0.000135

0.9475

1.0089

pass

three-time-point law with a three-valued baseline covariate, a repeated binary outcome that reads the two previous nodes, and monotone censoring

ey_regimen[treat then treat after an outcome @ t=3]

mean of the repeated outcome under the plan treat at the first time, then treat at each later time after an outcome of one at horizon t = 3

cleverly

-0.0014 to 0.000993

0.9325

0.9647

pass

Agreement with the canonical implementation#

Python property evidence, with comparator runs pending. The R ltmle 1.3-0 runs have not run on the declared draws, so this study publishes no paired verdict. The change that registers them adds the paired verdicts and the parity gate test_cleverly_reproduces_r_targeting_move_in_every_cell.

Theory properties#

property

cell

role

what was tested

what must hold

measured

result

double_robustness

always_t3__both_wrong

control

mean under always at horizon t = 3, repeated binary outcome: outcome regression of cell means on the baseline covariate alone, and intercept-only treatment and censoring mechanisms

bias interval must fall entirely outside the margin, and inside it around the exact limit of that fit, with the reported standard error still on the scale of the empirical spread

bias 0.0223 to 0.0260, margin 0.0068, SE ratio 1.2594, bias around its limit -0.0023 to 0.0014, margin 0.0068

pass

double_robustness

always_t3__mechanism_correct

positive

mean under always at horizon t = 3, repeated binary outcome: only the treatment and censoring mechanisms are correctly specified

bias interval inside the equivalence margin, with the reported standard error on the scale of the empirical spread

bias -0.0024 to 0.0011, margin 0.0062, SE ratio 0.9739

pass

double_robustness

always_t3__outcome_correct

positive

mean under always at horizon t = 3, repeated binary outcome: only the outcome regression is correctly specified

bias interval inside the equivalence margin, with the reported standard error on the scale of the empirical spread

bias -0.0031 to 0.000245, margin 0.0061, SE ratio 1.1849

pass

double_robustness

always_vs_never_t3__both_wrong

control

contrast of always against never at horizon t = 3, repeated binary outcome: outcome regression of cell means on the baseline covariate alone, and intercept-only treatment and censoring mechanisms

bias interval must fall entirely outside the margin, and inside it around the exact limit of that fit, with the reported standard error still on the scale of the empirical spread

bias 0.0747 to 0.0801, margin 0.0099, SE ratio 1.1883, bias around its limit -0.0043 to 0.0012, margin 0.0099

pass

double_robustness

always_vs_never_t3__mechanism_correct

positive

contrast of always against never at horizon t = 3, repeated binary outcome: only the treatment and censoring mechanisms are correctly specified

bias interval inside the equivalence margin, with the reported standard error on the scale of the empirical spread

bias -0.0028 to 0.0028, margin 0.0101, SE ratio 1.0117

pass

double_robustness

always_vs_never_t3__outcome_correct

positive

contrast of always against never at horizon t = 3, repeated binary outcome: only the outcome regression is correctly specified

bias interval inside the equivalence margin, with the reported standard error on the scale of the empirical spread

bias -0.0045 to 0.000955, margin 0.0099, SE ratio 1.0961

pass

double_robustness

never_t3__both_wrong

control

mean under never at horizon t = 3, repeated binary outcome: outcome regression of cell means on the baseline covariate alone, and intercept-only treatment and censoring mechanisms

bias interval must fall entirely outside the margin, and inside it around the exact limit of that fit, with the reported standard error still on the scale of the empirical spread

bias -0.0553 to -0.0513, margin 0.0072, SE ratio 1.1182, bias around its limit -0.000913 to 0.0031, margin 0.0072

pass

double_robustness

never_t3__mechanism_correct

positive

mean under never at horizon t = 3, repeated binary outcome: only the treatment and censoring mechanisms are correctly specified

bias interval inside the equivalence margin, with the reported standard error on the scale of the empirical spread

bias -0.0029 to 0.0016, margin 0.0080, SE ratio 1.0258

pass

double_robustness

never_t3__outcome_correct

positive

mean under never at horizon t = 3, repeated binary outcome: only the outcome regression is correctly specified

bias interval inside the equivalence margin, with the reported standard error on the scale of the empirical spread

bias -0.0019 to 0.0025, margin 0.0079, SE ratio 1.0069

pass

double_robustness

rule_t3__both_wrong

control

mean under the rule that treats after an outcome at horizon t = 3, repeated binary outcome: outcome regression of cell means on the baseline covariate alone, and intercept-only treatment and censoring mechanisms

bias interval must fall entirely outside the margin, and inside it around the exact limit of that fit, with the reported standard error still on the scale of the empirical spread

bias -0.0224 to -0.0190, margin 0.0063, SE ratio 0.9095, bias around its limit -0.0019 to 0.0016, margin 0.0063

pass

double_robustness

rule_t3__mechanism_correct

positive

mean under the rule that treats after an outcome at horizon t = 3, repeated binary outcome: only the treatment and censoring mechanisms are correctly specified

bias interval inside the equivalence margin, with the reported standard error on the scale of the empirical spread

bias -0.0024 to 0.0019, margin 0.0079, SE ratio 0.9913

pass

double_robustness

rule_t3__outcome_correct

positive

mean under the rule that treats after an outcome at horizon t = 3, repeated binary outcome: only the outcome regression is correctly specified

bias interval inside the equivalence margin, with the reported standard error on the scale of the empirical spread

bias -0.0021 to 0.0019, margin 0.0073, SE ratio 0.7386

pass

double_robustness

rule_vs_never_t3__both_wrong

control

contrast of the rule against never at horizon t = 3, repeated binary outcome: outcome regression of cell means on the baseline covariate alone, and intercept-only treatment and censoring mechanisms

bias interval must fall entirely outside the margin, and inside it around the exact limit of that fit, with the reported standard error still on the scale of the empirical spread

bias 0.0299 to 0.0352, margin 0.0096, SE ratio 1.0343, bias around its limit -0.0038 to 0.0014, margin 0.0096

pass

double_robustness

rule_vs_never_t3__mechanism_correct

positive

contrast of the rule against never at horizon t = 3, repeated binary outcome: only the treatment and censoring mechanisms are correctly specified

bias interval inside the equivalence margin, with the reported standard error on the scale of the empirical spread

bias -0.0026 to 0.0035, margin 0.0111, SE ratio 1.0223

pass

double_robustness

rule_vs_never_t3__outcome_correct

positive

contrast of the rule against never at horizon t = 3, repeated binary outcome: only the outcome regression is correctly specified

bias interval inside the equivalence margin, with the reported standard error on the scale of the empirical spread

bias -0.0034 to 0.0026, margin 0.0109, SE ratio 0.8856

pass

full_history_necessity

always_t3__full_history

positive

mean under always at horizon t = 3, repeated binary outcome: an outcome regression of cell means on the full history, with intercept-only mechanisms, so the regression alone carries the estimate

bias interval inside the equivalence margin

bias -0.000845 to 0.000921, margin 0.0030

pass

full_history_necessity

always_t3__markov_history

control

mean under always at horizon t = 3, repeated binary outcome: the same fit with the outcome regression on the previous node only, [W, Y_{t-1}, L_t], and the same intercept-only mechanisms

bias interval outside the margin, and inside it around the exact limit of the previous-node fit

bias 0.0204 to 0.0223, margin 0.0032, bias around its limit -0.0010 to 0.000904, margin 0.0032

pass

full_history_necessity

always_vs_never_t3__full_history

positive

contrast of always against never at horizon t = 3, repeated binary outcome: an outcome regression of cell means on the full history, with intercept-only mechanisms, so the regression alone carries the estimate

bias interval inside the equivalence margin

bias -0.0011 to 0.0018, margin 0.0048

pass

full_history_necessity

always_vs_never_t3__markov_history

control

contrast of always against never at horizon t = 3, repeated binary outcome: the same fit with the outcome regression on the previous node only, [W, Y_{t-1}, L_t], and the same intercept-only mechanisms

bias interval outside the margin, and inside it around the exact limit of the previous-node fit

bias 0.0693 to 0.0722, margin 0.0049, bias around its limit -0.0011 to 0.0018, margin 0.0049

pass

full_history_necessity

never_t3__full_history

positive

mean under never at horizon t = 3, repeated binary outcome: an outcome regression of cell means on the full history, with intercept-only mechanisms, so the regression alone carries the estimate

bias interval inside the equivalence margin

bias -0.0014 to 0.000824, margin 0.0038

pass

full_history_necessity

never_t3__markov_history

control

mean under never at horizon t = 3, repeated binary outcome: the same fit with the outcome regression on the previous node only, [W, Y_{t-1}, L_t], and the same intercept-only mechanisms

bias interval outside the margin, and inside it around the exact limit of the previous-node fit

bias -0.0505 to -0.0484, margin 0.0035, bias around its limit -0.0014 to 0.000680, margin 0.0035

pass

full_history_necessity

rule_t3__full_history

positive

mean under the rule that treats after an outcome at horizon t = 3, repeated binary outcome: an outcome regression of cell means on the full history, with intercept-only mechanisms, so the regression alone carries the estimate

bias interval inside the equivalence margin

bias -0.000663 to 0.0015, margin 0.0037

pass

full_history_necessity

rule_t3__markov_history

control

mean under the rule that treats after an outcome at horizon t = 3, repeated binary outcome: the same fit with the outcome regression on the previous node only, [W, Y_{t-1}, L_t], and the same intercept-only mechanisms

bias interval outside the margin, and inside it around the exact limit of the previous-node fit

bias -0.0270 to -0.0251, margin 0.0032, bias around its limit -0.000623 to 0.0013, margin 0.0032

pass

full_history_necessity

rule_vs_never_t3__full_history

positive

contrast of the rule against never at horizon t = 3, repeated binary outcome: an outcome regression of cell means on the full history, with intercept-only mechanisms, so the regression alone carries the estimate

bias interval inside the equivalence margin

bias -0.000855 to 0.0023, margin 0.0053

pass

full_history_necessity

rule_vs_never_t3__markov_history

control

contrast of the rule against never at horizon t = 3, repeated binary outcome: the same fit with the outcome regression on the previous node only, [W, Y_{t-1}, L_t], and the same intercept-only mechanisms

bias interval outside the margin, and inside it around the exact limit of the previous-node fit

bias 0.0220 to 0.0248, margin 0.0047, bias around its limit -0.000710 to 0.0021, margin 0.0047

pass

interval_calibration

always_t1__estimated_mechanisms

positive

mean under always at horizon t = 1, repeated binary outcome: n = 8,000, in sample, main-terms logistic mechanisms estimated, quasibinomial GLM outcome regressions, every horizon

SE-ratio and coverage intervals inside the calibration bands

coverage 0.9433 to 0.9560, SE ratio 0.9852 to 1.0279

pass

interval_calibration

always_t2__estimated_mechanisms

positive

always-treat risk at horizon two: n = 8,000, in sample, main-terms logistic mechanisms estimated, quasibinomial GLM outcome regressions, every horizon

SE-ratio and coverage intervals inside the calibration bands

coverage 0.9414 to 0.9543, SE ratio 0.9757 to 1.0168

pass

interval_calibration

always_t3__continuous_gaussian

positive

mean under always at horizon t = 3, repeated binary outcome: n = 8,000, the three-value outcome law, least-squares outcome regressions, main-terms logistic mechanisms estimated

SE-ratio and coverage intervals inside the calibration bands

coverage 0.9393 to 0.9524, SE ratio 0.9738 to 1.0138

pass

interval_calibration

always_t3__crossfit_boosted

positive

mean under always at horizon t = 3, repeated binary outcome: n = 8,000, five folds, main-terms logistic mechanisms estimated, a depth-2 booster of 50 rounds with an L2 penalty for both outcome learners

SE-ratio and coverage intervals inside the calibration bands

coverage 0.9406 to 0.9536, SE ratio 0.9811 to 1.0218

pass

interval_calibration

always_t3__crossfit_glm

positive

mean under always at horizon t = 3, repeated binary outcome: n = 8,000, five folds, main-terms logistic mechanisms estimated, quasibinomial GLM outcome regressions

SE-ratio and coverage intervals inside the calibration bands

coverage 0.9372 to 0.9505, SE ratio 0.9800 to 1.0222

pass

interval_calibration

always_t3__estimated_mechanisms

positive

mean under always at horizon t = 3, repeated binary outcome: n = 8,000, in sample, main-terms logistic mechanisms estimated, quasibinomial GLM outcome regressions, every horizon

SE-ratio and coverage intervals inside the calibration bands

coverage 0.9396 to 0.9527, SE ratio 0.9744 to 1.0143

pass

interval_calibration

always_t3__noise_control

control

mean under always at horizon t = 3, repeated binary outcome: a declared scale of independent noise is added to each estimate

the SE-ratio interval must fall below the calibration band

coverage 0.8230 to 0.8446, SE ratio 0.6879 to 0.7162

pass

interval_calibration

always_t3__shrunken_se_control

control

mean under always at horizon t = 3, repeated binary outcome: the reported standard errors are multiplied by a declared factor below one

the SE-ratio interval must fall below the calibration band

coverage 0.8153 to 0.8373, SE ratio 0.6821 to 0.7106

pass

interval_calibration

always_vs_never_t1__estimated_mechanisms

positive

contrast of always against never at horizon t = 1, repeated binary outcome: n = 8,000, in sample, main-terms logistic mechanisms estimated, quasibinomial GLM outcome regressions, every horizon

SE-ratio and coverage intervals inside the calibration bands

coverage 0.9361 to 0.9496, SE ratio 0.9616 to 1.0010

pass

interval_calibration

always_vs_never_t2__estimated_mechanisms

positive

contrast of always against never at horizon t = 2, repeated binary outcome: n = 8,000, in sample, main-terms logistic mechanisms estimated, quasibinomial GLM outcome regressions, every horizon

SE-ratio and coverage intervals inside the calibration bands

coverage 0.9426 to 0.9554, SE ratio 0.9803 to 1.0200

pass

interval_calibration

always_vs_never_t3__continuous_gaussian

positive

contrast of always against never at horizon t = 3, repeated binary outcome: n = 8,000, the three-value outcome law, least-squares outcome regressions, main-terms logistic mechanisms estimated

SE-ratio and coverage intervals inside the calibration bands

coverage 0.9414 to 0.9543, SE ratio 0.9796 to 1.0200

pass

interval_calibration

always_vs_never_t3__crossfit_boosted

positive

contrast of always against never at horizon t = 3, repeated binary outcome: n = 8,000, five folds, main-terms logistic mechanisms estimated, a depth-2 booster of 50 rounds with an L2 penalty for both outcome learners

SE-ratio and coverage intervals inside the calibration bands

coverage 0.9402 to 0.9532, SE ratio 0.9821 to 1.0225

pass

interval_calibration

always_vs_never_t3__crossfit_glm

positive

contrast of always against never at horizon t = 3, repeated binary outcome: n = 8,000, five folds, main-terms logistic mechanisms estimated, quasibinomial GLM outcome regressions

SE-ratio and coverage intervals inside the calibration bands

coverage 0.9417 to 0.9545, SE ratio 0.9747 to 1.0145

pass

interval_calibration

always_vs_never_t3__estimated_mechanisms

positive

contrast of always against never at horizon t = 3, repeated binary outcome: n = 8,000, in sample, main-terms logistic mechanisms estimated, quasibinomial GLM outcome regressions, every horizon

SE-ratio and coverage intervals inside the calibration bands

coverage 0.9435 to 0.9562, SE ratio 0.9808 to 1.0221

pass

interval_calibration

always_vs_never_t3__noise_control

control

contrast of always against never at horizon t = 3, repeated binary outcome: a declared scale of independent noise is added to each estimate

the SE-ratio interval must fall below the calibration band

coverage 0.8264 to 0.8477, SE ratio 0.6960 to 0.7257

pass

interval_calibration

always_vs_never_t3__shrunken_se_control

control

contrast of always against never at horizon t = 3, repeated binary outcome: the reported standard errors are multiplied by a declared factor below one

the SE-ratio interval must fall below the calibration band

coverage 0.8146 to 0.8365, SE ratio 0.6868 to 0.7153

pass

interval_calibration

never_t1__estimated_mechanisms

positive

mean under never at horizon t = 1, repeated binary outcome: n = 8,000, in sample, main-terms logistic mechanisms estimated, quasibinomial GLM outcome regressions, every horizon

SE-ratio and coverage intervals inside the calibration bands

coverage 0.9373 to 0.9507, SE ratio 0.9601 to 1.0001

pass

interval_calibration

never_t2__estimated_mechanisms

positive

mean under never at horizon t = 2, repeated binary outcome: n = 8,000, in sample, main-terms logistic mechanisms estimated, quasibinomial GLM outcome regressions, every horizon

SE-ratio and coverage intervals inside the calibration bands

coverage 0.9419 to 0.9548, SE ratio 0.9841 to 1.0251

pass

interval_calibration

never_t3__continuous_gaussian

positive

mean under never at horizon t = 3, repeated binary outcome: n = 8,000, the three-value outcome law, least-squares outcome regressions, main-terms logistic mechanisms estimated

SE-ratio and coverage intervals inside the calibration bands

coverage 0.9459 to 0.9583, SE ratio 0.9864 to 1.0274

pass

interval_calibration

never_t3__crossfit_boosted

positive

mean under never at horizon t = 3, repeated binary outcome: n = 8,000, five folds, main-terms logistic mechanisms estimated, a depth-2 booster of 50 rounds with an L2 penalty for both outcome learners

SE-ratio and coverage intervals inside the calibration bands

coverage 0.9441 to 0.9567, SE ratio 0.9877 to 1.0297

pass

interval_calibration

never_t3__crossfit_glm

positive

mean under never at horizon t = 3, repeated binary outcome: n = 8,000, five folds, main-terms logistic mechanisms estimated, quasibinomial GLM outcome regressions

SE-ratio and coverage intervals inside the calibration bands

coverage 0.9422 to 0.9550, SE ratio 0.9726 to 1.0129

pass

interval_calibration

never_t3__estimated_mechanisms

positive

mean under never at horizon t = 3, repeated binary outcome: n = 8,000, in sample, main-terms logistic mechanisms estimated, quasibinomial GLM outcome regressions, every horizon

SE-ratio and coverage intervals inside the calibration bands

coverage 0.9458 to 0.9582, SE ratio 0.9768 to 1.0176

pass

interval_calibration

never_t3__noise_control

control

mean under never at horizon t = 3, repeated binary outcome: a declared scale of independent noise is added to each estimate

the SE-ratio interval must fall below the calibration band

coverage 0.8165 to 0.8384, SE ratio 0.6824 to 0.7105

pass

interval_calibration

never_t3__shrunken_se_control

control

mean under never at horizon t = 3, repeated binary outcome: the reported standard errors are multiplied by a declared factor below one

the SE-ratio interval must fall below the calibration band

coverage 0.8157 to 0.8376, SE ratio 0.6837 to 0.7121

pass

interval_calibration

rule_t2__estimated_mechanisms

positive

mean under the rule that treats after an outcome at horizon t = 2, repeated binary outcome: n = 8,000, in sample, main-terms logistic mechanisms estimated, quasibinomial GLM outcome regressions, every horizon

SE-ratio and coverage intervals inside the calibration bands

coverage 0.9418 to 0.9547, SE ratio 0.9909 to 1.0329

pass

interval_calibration

rule_t3__continuous_gaussian

positive

mean under the rule that treats after an outcome at horizon t = 3, repeated binary outcome: n = 8,000, the three-value outcome law, least-squares outcome regressions, main-terms logistic mechanisms estimated

SE-ratio and coverage intervals inside the calibration bands

coverage 0.9396 to 0.9527, SE ratio 0.9666 to 1.0077

pass

interval_calibration

rule_t3__crossfit_boosted

positive

mean under the rule that treats after an outcome at horizon t = 3, repeated binary outcome: n = 8,000, five folds, main-terms logistic mechanisms estimated, a depth-2 booster of 50 rounds with an L2 penalty for both outcome learners

SE-ratio and coverage intervals inside the calibration bands

coverage 0.9396 to 0.9527, SE ratio 0.9885 to 1.0307

pass

interval_calibration

rule_t3__crossfit_glm

positive

mean under the rule that treats after an outcome at horizon t = 3, repeated binary outcome: n = 8,000, five folds, main-terms logistic mechanisms estimated, quasibinomial GLM outcome regressions

SE-ratio and coverage intervals inside the calibration bands

coverage 0.9409 to 0.9538, SE ratio 0.9794 to 1.0214

pass

interval_calibration

rule_t3__estimated_mechanisms

positive

mean under the rule that treats after an outcome at horizon t = 3, repeated binary outcome: n = 8,000, in sample, main-terms logistic mechanisms estimated, quasibinomial GLM outcome regressions, every horizon

SE-ratio and coverage intervals inside the calibration bands

coverage 0.9370 to 0.9504, SE ratio 0.9642 to 1.0039

pass

interval_calibration

rule_t3__noise_control

control

mean under the rule that treats after an outcome at horizon t = 3, repeated binary outcome: a declared scale of independent noise is added to each estimate

the SE-ratio interval must fall below the calibration band

coverage 0.8173 to 0.8391, SE ratio 0.6858 to 0.7153

pass

interval_calibration

rule_t3__shrunken_se_control

control

mean under the rule that treats after an outcome at horizon t = 3, repeated binary outcome: the reported standard errors are multiplied by a declared factor below one

the SE-ratio interval must fall below the calibration band

coverage 0.8125 to 0.8346, SE ratio 0.6748 to 0.7025

pass

interval_calibration

rule_vs_never_t2__estimated_mechanisms

positive

contrast of the rule against never at horizon t = 2, repeated binary outcome: n = 8,000, in sample, main-terms logistic mechanisms estimated, quasibinomial GLM outcome regressions, every horizon

SE-ratio and coverage intervals inside the calibration bands

coverage 0.9466 to 0.9589, SE ratio 0.9877 to 1.0282

pass

interval_calibration

rule_vs_never_t3__continuous_gaussian

positive

contrast of the rule against never at horizon t = 3, repeated binary outcome: n = 8,000, the three-value outcome law, least-squares outcome regressions, main-terms logistic mechanisms estimated

SE-ratio and coverage intervals inside the calibration bands

coverage 0.9425 to 0.9552, SE ratio 0.9862 to 1.0270

pass

interval_calibration

rule_vs_never_t3__crossfit_boosted

positive

contrast of the rule against never at horizon t = 3, repeated binary outcome: n = 8,000, five folds, main-terms logistic mechanisms estimated, a depth-2 booster of 50 rounds with an L2 penalty for both outcome learners

SE-ratio and coverage intervals inside the calibration bands

coverage 0.9437 to 0.9563, SE ratio 0.9875 to 1.0286

pass

interval_calibration

rule_vs_never_t3__crossfit_glm

positive

contrast of the rule against never at horizon t = 3, repeated binary outcome: n = 8,000, five folds, main-terms logistic mechanisms estimated, quasibinomial GLM outcome regressions

SE-ratio and coverage intervals inside the calibration bands

coverage 0.9431 to 0.9558, SE ratio 0.9793 to 1.0201

pass

interval_calibration

rule_vs_never_t3__estimated_mechanisms

positive

contrast of the rule against never at horizon t = 3, repeated binary outcome: n = 8,000, in sample, main-terms logistic mechanisms estimated, quasibinomial GLM outcome regressions, every horizon

SE-ratio and coverage intervals inside the calibration bands

coverage 0.9421 to 0.9549, SE ratio 0.9741 to 1.0141

pass

interval_calibration

rule_vs_never_t3__noise_control

control

contrast of the rule against never at horizon t = 3, repeated binary outcome: a declared scale of independent noise is added to each estimate

the SE-ratio interval must fall below the calibration band

coverage 0.8255 to 0.8469, SE ratio 0.6952 to 0.7249

pass

interval_calibration

rule_vs_never_t3__shrunken_se_control

control

contrast of the rule against never at horizon t = 3, repeated binary outcome: the reported standard errors are multiplied by a declared factor below one

the SE-ratio interval must fall below the calibration band

coverage 0.8182 to 0.8400, SE ratio 0.6821 to 0.7102

pass

outcome_history_necessity

always_t3__history_free

control

mean under always at horizon t = 3, repeated binary outcome: an end-of-study fit with no earlier outcome in any history, cell-mean outcome regressions: the earlier outcomes are confounders, and the fit leaves them out of the outcome regression and both mechanisms

bias interval outside the margin, and inside it around the coarse g-formula

bias 0.0163 to 0.0201, margin 0.0065, bias around its limit -0.000997 to 0.0029, margin 0.0065

pass

outcome_history_necessity

always_t3__repeated

positive

mean under always at horizon t = 3, repeated binary outcome: the repeated-outcome fit, mechanisms estimated, GLM outcome regressions

bias interval inside the equivalence margin

bias -0.000740 to 0.0028, margin 0.0059

pass

outcome_history_necessity

always_vs_never_t3__history_free

control

contrast of always against never at horizon t = 3, repeated binary outcome: an end-of-study fit with no earlier outcome in any history, cell-mean outcome regressions: the earlier outcomes are confounders, and the fit leaves them out of the outcome regression and both mechanisms

bias interval outside the margin, and inside it around the coarse g-formula

bias 0.0570 to 0.0627, margin 0.0095, bias around its limit -0.0028 to 0.0029, margin 0.0095

pass

outcome_history_necessity

always_vs_never_t3__repeated

positive

contrast of always against never at horizon t = 3, repeated binary outcome: the repeated-outcome fit, mechanisms estimated, GLM outcome regressions

bias interval inside the equivalence margin

bias -0.0021 to 0.0034, margin 0.0093

pass

outcome_history_necessity

never_t3__history_free

control

mean under never at horizon t = 3, repeated binary outcome: an end-of-study fit with no earlier outcome in any history, cell-mean outcome regressions: the earlier outcomes are confounders, and the fit leaves them out of the outcome regression and both mechanisms

bias interval outside the margin, and inside it around the coarse g-formula

bias -0.0438 to -0.0395, margin 0.0073, bias around its limit -0.0013 to 0.0030, margin 0.0073

pass

outcome_history_necessity

never_t3__repeated

positive

mean under never at horizon t = 3, repeated binary outcome: the repeated-outcome fit, mechanisms estimated, GLM outcome regressions

bias interval inside the equivalence margin

bias -0.0018 to 0.0026, margin 0.0073

pass

repeated_outcome_necessity

always_t2__absorbing_reading

control

always-treat risk at horizon two: an end-of-study fit of the maximum of the outcomes through the horizon, cell means with a GLM on an unseen cell

bias interval outside the margin, and inside it around the maximum’s own truth

bias 0.1123 to 0.1131, margin 0.0020, bias around its limit -0.000626 to 0.000169, margin 0.0020

pass

repeated_outcome_necessity

always_t2__repeated

positive

always-treat risk at horizon two: the repeated-outcome fit, mechanisms estimated, GLM outcome regressions

bias interval inside the equivalence margin

bias -0.000606 to 0.000107, margin 0.0018

pass

repeated_outcome_necessity

always_t3__absorbing_reading

control

mean under always at horizon t = 3, repeated binary outcome: an end-of-study fit of the maximum of the outcomes through the horizon, cell means with a GLM on an unseen cell

bias interval outside the margin, and inside it around the maximum’s own truth

bias 0.1648 to 0.1660, margin 0.0032, bias around its limit -0.000676 to 0.000586, margin 0.0032

pass

repeated_outcome_necessity

always_t3__repeated

positive

mean under always at horizon t = 3, repeated binary outcome: the repeated-outcome fit, mechanisms estimated, GLM outcome regressions

bias interval inside the equivalence margin

bias -0.000343 to 0.000828, margin 0.0030

pass

repeated_outcome_necessity

never_t2__absorbing_reading

control

mean under never at horizon t = 2, repeated binary outcome: an end-of-study fit of the maximum of the outcomes through the horizon, cell means with a GLM on an unseen cell

bias interval outside the margin, and inside it around the maximum’s own truth

bias 0.1406 to 0.1416, margin 0.0025, bias around its limit -0.000640 to 0.000349, margin 0.0025

pass

repeated_outcome_necessity

never_t2__repeated

positive

mean under never at horizon t = 2, repeated binary outcome: the repeated-outcome fit, mechanisms estimated, GLM outcome regressions

bias interval inside the equivalence margin

bias -0.000646 to 0.000323, margin 0.0025

pass

repeated_outcome_necessity

never_t3__absorbing_reading

control

mean under never at horizon t = 3, repeated binary outcome: an end-of-study fit of the maximum of the outcomes through the horizon, cell means with a GLM on an unseen cell

bias interval outside the margin, and inside it around the maximum’s own truth

bias 0.1769 to 0.1781, margin 0.0030, bias around its limit -0.000798 to 0.000386, margin 0.0030

pass

repeated_outcome_necessity

never_t3__repeated

positive

mean under never at horizon t = 3, repeated binary outcome: the repeated-outcome fit, mechanisms estimated, GLM outcome regressions

bias interval inside the equivalence margin

bias -0.000917 to 0.000528, margin 0.0037

pass

repeated_outcome_necessity

rule_t2__absorbing_reading

control

mean under the rule that treats after an outcome at horizon t = 2, repeated binary outcome: an end-of-study fit of the maximum of the outcomes through the horizon, cell means with a GLM on an unseen cell

bias interval outside the margin, and inside it around the maximum’s own truth

bias 0.1123 to 0.1132, margin 0.0022, bias around its limit -0.000590 to 0.000257, margin 0.0022

pass

repeated_outcome_necessity

rule_t2__repeated

positive

mean under the rule that treats after an outcome at horizon t = 2, repeated binary outcome: the repeated-outcome fit, mechanisms estimated, GLM outcome regressions

bias interval inside the equivalence margin

bias -0.000592 to 0.000214, margin 0.0021

pass

repeated_outcome_necessity

rule_t3__absorbing_reading

control

mean under the rule that treats after an outcome at horizon t = 3, repeated binary outcome: an end-of-study fit of the maximum of the outcomes through the horizon, cell means with a GLM on an unseen cell

bias interval outside the margin, and inside it around the maximum’s own truth

bias 0.2234 to 0.2245, margin 0.0028, bias around its limit -0.000733 to 0.000354, margin 0.0028

pass

repeated_outcome_necessity

rule_t3__repeated

positive

mean under the rule that treats after an outcome at horizon t = 3, repeated binary outcome: the repeated-outcome fit, mechanisms estimated, GLM outcome regressions

bias interval inside the equivalence margin

bias -0.000594 to 0.000724, margin 0.0034

pass

rule_necessity

rule_t2__declared

positive

mean under the rule that treats after an outcome at horizon t = 2, repeated binary outcome: the declared covariate-dependent rule assigns both treatment arms

bias interval inside the equivalence margin

bias -0.0011 to 0.000817, margin 0.0042

pass

rule_necessity

rule_t2__reversed_rule

control

mean under the rule that treats after an outcome at horizon t = 2, repeated binary outcome: the same fit treats after a zero outcome instead of after an outcome of one

bias interval must fall entirely outside the margin, and inside it around the reversed rule’s own truth

bias -0.0570 to -0.0551, margin 0.0040, bias around its limit -0.000339 to 0.0015, margin 0.0040

pass

rule_necessity

rule_t3__declared

positive

mean under the rule that treats after an outcome at horizon t = 3, repeated binary outcome: the declared covariate-dependent rule assigns both treatment arms

bias interval inside the equivalence margin

bias -0.0017 to 0.0017, margin 0.0073

pass

rule_necessity

rule_t3__reversed_rule

control

mean under the rule that treats after an outcome at horizon t = 3, repeated binary outcome: the same fit treats after a zero outcome instead of after an outcome of one

bias interval must fall entirely outside the margin, and inside it around the reversed rule’s own truth

bias -0.0608 to -0.0578, margin 0.0064, bias around its limit -0.0014 to 0.0015, margin 0.0064

pass

simultaneous_coverage

all_reported__pointwise_joint_control

control

every parameter the calibration fit reports: the pointwise 95% intervals of the same fits, read jointly

joint coverage upper endpoint must fall below the nominal rate

joint coverage 0.5830 to 0.6114

pass

simultaneous_coverage

all_reported__simultaneous_band

positive

every parameter the calibration fit reports: the max-t multiplier band over every estimand the law reports, from the same-row centered influence curves

joint coverage interval inside the calibration coverage band

joint coverage 0.9339 to 0.9476

pass

small_sample_calibration

always_t3__continuous_gaussian

diagnostic

mean under always at horizon t = 3, repeated binary outcome: the in-sample continuous calibration arm at n = 2,000

reported, no verdict

SE ratio 0.8986 to 0.9744

reported

small_sample_calibration

always_t3__estimated_mechanisms

diagnostic

mean under always at horizon t = 3, repeated binary outcome: the in-sample binary calibration arm at n = 2,000

reported, no verdict

SE ratio 0.9470 to 1.0289

reported

small_sample_calibration

always_vs_never_t3__continuous_gaussian

diagnostic

contrast of always against never at horizon t = 3, repeated binary outcome: the in-sample continuous calibration arm at n = 2,000

reported, no verdict

SE ratio 0.9102 to 0.9898

reported

small_sample_calibration

always_vs_never_t3__estimated_mechanisms

diagnostic

contrast of always against never at horizon t = 3, repeated binary outcome: the in-sample binary calibration arm at n = 2,000

reported, no verdict

SE ratio 0.9254 to 1.0030

reported

small_sample_calibration

never_t3__continuous_gaussian

diagnostic

mean under never at horizon t = 3, repeated binary outcome: the in-sample continuous calibration arm at n = 2,000

reported, no verdict

SE ratio 0.9200 to 0.9998

reported

small_sample_calibration

never_t3__estimated_mechanisms

diagnostic

mean under never at horizon t = 3, repeated binary outcome: the in-sample binary calibration arm at n = 2,000

reported, no verdict

SE ratio 0.9088 to 0.9852

reported

small_sample_calibration

rule_t3__continuous_gaussian

diagnostic

mean under the rule that treats after an outcome at horizon t = 3, repeated binary outcome: the in-sample continuous calibration arm at n = 2,000

reported, no verdict

SE ratio 0.9261 to 1.0087

reported

small_sample_calibration

rule_t3__estimated_mechanisms

diagnostic

mean under the rule that treats after an outcome at horizon t = 3, repeated binary outcome: the in-sample binary calibration arm at n = 2,000

reported, no verdict

SE ratio 0.9789 to 1.0658

reported

small_sample_calibration

rule_vs_never_t3__continuous_gaussian

diagnostic

contrast of the rule against never at horizon t = 3, repeated binary outcome: the in-sample continuous calibration arm at n = 2,000

reported, no verdict

SE ratio 0.9162 to 1.0025

reported

small_sample_calibration

rule_vs_never_t3__estimated_mechanisms

diagnostic

contrast of the rule against never at horizon t = 3, repeated binary outcome: the in-sample binary calibration arm at n = 2,000

reported, no verdict

SE ratio 0.9588 to 1.0429

reported

targeting_necessity

always_t3__targeted

positive

mean under always at horizon t = 3, repeated binary outcome: the estimator fluctuates a misspecified outcome model, so targeting does all the adjusting

bias interval inside the equivalence margin

bias 0.000520 to 0.0037, margin 0.0062

pass

targeting_necessity

always_t3__untargeted

control

mean under always at horizon t = 3, repeated binary outcome: the iterated cell means on the baseline covariate among the units that followed the plan, with no fluctuation step

bias interval must fall entirely outside the margin, and inside it around the baseline-only plug-in limit

bias 0.0247 to 0.0282, margin 0.0068, bias around its limit 0.000122 to 0.0036, margin 0.0068

pass

targeting_necessity

always_vs_never_t3__targeted

positive

contrast of always against never at horizon t = 3, repeated binary outcome: the estimator fluctuates a misspecified outcome model, so targeting does all the adjusting

bias interval inside the equivalence margin

bias -0.000067 to 0.0051, margin 0.0101

pass

targeting_necessity

always_vs_never_t3__untargeted

control

contrast of always against never at horizon t = 3, repeated binary outcome: the iterated cell means on the baseline covariate among the units that followed the plan, with no fluctuation step

bias interval must fall entirely outside the margin, and inside it around the baseline-only plug-in limit

bias 0.0779 to 0.0831, margin 0.0100, bias around its limit -0.0010 to 0.0041, margin 0.0100

pass

targeting_necessity

never_t3__targeted

positive

mean under never at horizon t = 3, repeated binary outcome: the estimator fluctuates a misspecified outcome model, so targeting does all the adjusting

bias interval inside the equivalence margin

bias -0.0024 to 0.0016, margin 0.0078

pass

targeting_necessity

never_t3__untargeted

control

mean under never at horizon t = 3, repeated binary outcome: the iterated cell means on the baseline covariate among the units that followed the plan, with no fluctuation step

bias interval must fall entirely outside the margin, and inside it around the baseline-only plug-in limit

bias -0.0558 to -0.0522, margin 0.0070, bias around its limit -0.0015 to 0.0021, margin 0.0070

pass

targeting_necessity

rule_t3__targeted

positive

mean under the rule that treats after an outcome at horizon t = 3, repeated binary outcome: the estimator fluctuates a misspecified outcome model, so targeting does all the adjusting

bias interval inside the equivalence margin

bias -0.000839 to 0.0031, margin 0.0076

pass

targeting_necessity

rule_t3__untargeted

control

mean under the rule that treats after an outcome at horizon t = 3, repeated binary outcome: the iterated cell means on the baseline covariate among the units that followed the plan, with no fluctuation step

bias interval must fall entirely outside the margin, and inside it around the baseline-only plug-in limit

bias -0.0224 to -0.0193, margin 0.0059, bias around its limit -0.000531 to 0.0025, margin 0.0059

pass

targeting_necessity

rule_vs_never_t3__targeted

positive

contrast of the rule against never at horizon t = 3, repeated binary outcome: the estimator fluctuates a misspecified outcome model, so targeting does all the adjusting

bias interval inside the equivalence margin

bias -0.0013 to 0.0043, margin 0.0109

pass

targeting_necessity

rule_vs_never_t3__untargeted

control

contrast of the rule against never at horizon t = 3, repeated binary outcome: the iterated cell means on the baseline covariate among the units that followed the plan, with no fluctuation step

bias interval must fall entirely outside the margin, and inside it around the baseline-only plug-in limit

bias 0.0308 to 0.0355, margin 0.0090, bias around its limit -0.0016 to 0.0030, margin 0.0090

pass

The property families draw from their own streams of make_longitudinal_repeated. Their draws differ from the primary draws. The table above lists every cell. This section states what each family tests.

family

what it tests

size

interval_calibration

pointwise coverage and SE ratio inside the calibration bands. The cells are in-sample with estimated mechanisms, cross-fitted GLM, cross-fitted boosted trees, and a continuous outcome. The in-sample cells cover every horizon, \(t = 1, 2, 3\). A shrunken-SE control and a noise control must fail the same bands

\(n\) = 8,000, 8,000 replications

small_sample_calibration

the in-sample and continuous arms refitted at \(n\) = 2,000. The role is diagnostic. The table reports these cells and no rule gates them

\(n\) = 2,000, 2,000 replications

double_robustness

mechanism_correct: bias inside the margin when the outcome regression reads \(W\) alone and the mechanisms are correct. outcome_correct: bias inside the margin when the outcome regression reads the full history and the mechanisms read \(W\) alone. both_wrong: the control with a \(W\) regression and intercept-only mechanisms must miss the truth and reach its exact limit. A static plan has no fluctuation in this fit. The rule has one, and it moves the limit by 0.046 empirical standard deviations of the rule’s mean at \(t = 3\) (0.031 for its contrast). Replications cannot separate that move from the plug-in limit, because the 99% bias interval at 1,400 replications is 0.069 standard deviations wide on each side. The claim that the rule’s fluctuation moves the fit rests on test_the_limit_functional_reproduces_cleverly_on_a_sample, which matches a fit to the limit functional on one sample to \(10^{-10}\)

\(n\) = 2,000, 1,400 replications

targeting_necessity

the targeted fit against a plug-in with no fluctuation. The plug-in must move the estimate by 0.25 empirical standard deviations of the targeted arm and reach the exact \(W\)-only g-formula

\(n\) = 2,000, 1,600 replications

simultaneous_coverage

the default band over all 15 reported parameters, against its pointwise control

\(n\) = 8,000, 8,000 replications

rule_necessity

the declared rule against its reverse, which treats after a zero outcome. The reversed rule must miss the declared rule’s truth and reach the truth of the reversed rule

\(n\) = 2,000, 2,000 replications

repeated_outcome_necessity (N1)

an absorbing reading of the outcome, which fits \(\max_{s \le h} Y_s\). The control must miss the truth and reach the cumulative-maximum limit. Its outcome learner is a cell-means regression with a GLM fallback on an unseen cell

\(n\) = 8,000, 2,800 replications

outcome_history_necessity (N2)

a fit that leaves every \(Y_s\) out of the history, so the earlier outcomes act as confounders. The control must miss the truth and reach the coarse g-formula limit

\(n\) = 2,000, 1,200 replications

full_history_necessity (N3)

an outcome regression on the full history against one on \([W, Y_{t-1}, L_t]\), both with intercept-only mechanisms. The control must miss the truth and reach the exact limit of the single-fold fit

\(n\) = 8,000, 1,200 replications

The in-sample cells use \(n\) = 8,000. At \(n\) = 2,000 the standard error runs a few percent below the sampling spread for the rule. The ratio moves toward 1 at the \(1/n\) rate of in-sample fitting. The module tests/studies/ltmle_repeated_properties.py records the pilots behind these sizes. The small_sample_calibration cells report the shortfall at \(n\) = 2,000.

The calibration budget is the smallest multiple of 400 replications at which the 28 gated cells pass together with probability 0.95. The probability pools the cells of each arm. It takes the arm mean from the pilot and adds the noise of that mean. It sets the spread between cells at its 80% upper bound of 0.0059. The probability is 0.952 at 8,000 replications.

The sizes of the other families come from their bias checks. Each family has its own mean. The spread between cells is at its 80% upper bound of 0.0325. Each family takes the smallest multiple of 200 replications at which it passes with probability 0.991, the sixth root of 0.95. The six families then pass together with probability 0.961. A reading that gives every family one mean gives 0.994 at these sizes.

Measured values#

Names beginning margin: are thresholds declared before the run. Everything else is measured from the committed results and checked at the precision printed.

quantity

value

source

replicates

2400

primary replications per scenario

n

3000

observations per primary replication

independent_tests_total

13

implementation-estimand tests against the truth

independent_tests_passed

13

of those, passing

paired_tests_total

0

paired comparisons with R ltmle

paired_tests_passed

0

of those, passing

property_cells_total

97

repeated-sampling property cells, reported cells excluded

property_cells_passed

97

cells whose own and family verdicts pass

property_cells_reported

10

cells reported and not gated, as the small_sample_calibration diagnostics

max_standardized_bias

0.0426

largest absolute primary bias in empirical standard deviations

min_coverage

0.9325

lowest measured primary-study coverage

min_se_ratio_ci_lower

0.9286

lowest bootstrap primary SE-ratio endpoint

max_se_ratio_ci_upper

1.0674

highest bootstrap primary SE-ratio endpoint

margin:alpha

0.0500

nominal size of the reported intervals, and the family level of the rule

margin:bootstrap_replicates

10000

resamples behind every bootstrap interval

margin:calibration_coverage_lower

0.9200

calibration-cell coverage band, lower limit

margin:calibration_coverage_upper

0.9800

calibration-cell coverage band, upper limit

margin:calibration_noninferiority

0.0500

largest external-comparison calibration excess bound

margin:calibration_se_ratio_lower

0.9300

calibration-cell SE-ratio band, lower limit

margin:calibration_se_ratio_upper

1.0700

calibration-cell SE-ratio band, upper limit

margin:confidence_level

0.9900

confidence level of every Monte Carlo interval

margin:coverage_floor

0.9000

validity floor the coverage lower endpoint must clear

margin:coverage_noninferiority

-0.0250

smallest external-comparison coverage difference bound

margin:excluded_slope

-0.2500

slower rate a root-n interval must exclude. No cell of this study reads it

margin:minimum_power

0.8000

rejection lower bound a power cell must clear. No cell of this study reads it

margin:nominal_coverage

0.9500

nominal coverage those intervals claim

margin:over_coverage_ceiling

0.9900

above this, coverage is conservative rather than invalid

margin:paired_difference

0.1500

paired similarity margin, in pooled empirical standard deviations

margin:rmse_noninferiority

1.1000

largest external-comparison RMSE ratio bound

margin:root_n_slope

-0.5000

contraction rate root-n asymptotics predict. No cell of this study reads it

margin:root_n_slope_lower

-0.6250

accepted root-n slope band, lower limit. No cell of this study reads it

margin:root_n_slope_upper

-0.3750

accepted root-n slope band, upper limit. No cell of this study reads it

margin:se_ratio_sanity_lower

0.8000

SE-ratio screen, lower limit

margin:se_ratio_sanity_upper

1.2000

SE-ratio screen, upper limit

margin:standardized_bias

0.2500

bias equivalence margin, in empirical standard deviations

margin:type_i_ceiling

0.1000

the rate a positive cell must bound and a control must exceed. No cell of this study reads it

margin:union_model_se_lower

0.1000

union-model SE-ratio screen, lower limit

margin:union_model_se_upper

10

union-model SE-ratio screen, upper limit

margin:shrunken_se_factor

0.7000

factor the shrunken-SE control multiplies the standard error by

margin:necessity_displacement

0.2500

smallest paired displacement of a necessity control, in empirical standard deviations

margin:targeting_displacement

0.2500

smallest displacement of the untargeted plug-in from the targeted fit, in empirical standard deviations of the targeted arm

Limitations#

limit

what it means for use

one law with three nodes and a binary outcome

the continuous outcome has one calibration arm, and the rate in \(n\) is not measured

the comparator runs are pending

the targeting_necessity family carries the claim that targeting moves the estimate. The pending parity gate test_cleverly_reproduces_r_targeting_move_in_every_cell adds a check against R. In each cell the root-mean-square difference from R must stay below 1% of R’s root-mean-square targeting move. No replication may differ from R by more than 1% of R’s mean standard error

the declared comparison fixes the mechanisms

the paired margins alone cannot separate an untargeted plug-in from the targeted fit, because the plug-in is nearly unbiased on this law. The comparison does not claim parity for learned treatment or censoring models

the in-sample interval is mildly anticonservative at \(n\) = 2,000

the small_sample_calibration cells report the shortfall and no rule gates them. The gated calibration cells draw \(n\) = 8,000. The primary cells draw \(n\) = 3,000 and answer to the coverage floor

the cross-fitted learners are one GLM and one shallow booster

the study does not cover a larger learner library or a different fold count

the absorbing, history-free and Markov controls read exact limits of this law

they show that the repeated reading, the earlier outcomes and the depth of the outcome regression matter here. They do not bound the difference on another law

positivity is bounded away from zero, not absent

at \(t = 3\) the smallest cumulative mechanism product among followers is 0.025, and at most 2.2% of the followers fall below 0.05. No cell validates active truncation or near-positivity behavior

the second-order dependence acts at node 3 only

the law has three nodes, so the depth-two terms act at the last node. No cell reads a longer history

no recurrent-event or truncation-by-death law

the parameter is the mean in a population where censoring is prevented

The causal interpretation requires consistency, sequential exchangeability, longitudinal positivity, and conditionally independent censoring.

Reproduction#

The fixture README gives the regeneration commands. The manifest records the pending comparator, the declared R sources, the seeds and the artifact hashes. The replications and property results carry every published row.